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When Regulatory Systems Are Misaligned, Pain Persists When sleep, stress physiology, and metabolic regulation are compromised simultaneously, the bodys capacity to resolve inflammation and repair tissue declinesregardless of the intervention used

doi:10.3346/jkms.2015.30.9.1213 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( Source: Wieers, Michiel L A J et al

Ann N Y Acad Sci 939:162178 Calabrese V, Ravagna A, Colombrita C, Scapagnini G, Guagliano E, Calvani M, Butterfield DA, Giuffrida Stella AM (2005) Acetylcarnitine induces heme oxygenase in rat astrocytes and protects against oxidative stress: involvement of the transcription factor Nrf2

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