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Approximately 510% of APAP undergoes hepatic metabolism by cytochrome CYP 2E1, as a consequence, a highly reactive and harmful metabolite known as N -acetyl-para-benzoquinone imine (NAPQI), Fig
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Last years award for paleogenomics falls more toward the former, suggesting an advance with a more clinical focus could well be in the Nobel Assemblys sights this year
Acknowledgments The authors thank Meira Ben-Gad for editorial assistance