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NHS approach to B12 deficiency: NICE Clinical Knowledge Summaries recommend investigating B12 deficiency in patients presenting with macrocytic anaemia, unexplained neurological symptoms, or risk factors including pernicious anaemia, gastrectomy, malabsorption disorders, metformin use, proton pump inhibitors, or nitrous oxide exposure
For instance, one study noted that individuals who regularly took vitamin B12 supplements gained between 2.5 to 17 fewer pounds (1.2 to 7.7 kg) over a decade than those who didn't supplement
Vitamin B 12 from foods appear to have different absorption rates with better absorption from chicken and beef as compared to eggs
Vegans require the same 1.5 mcg daily but must obtain it through fortified foods or supplements