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According to a report from the World Health Organization, In humans, CBD exhibits no effects indicative of any abuse or dependence potential To date, there is no evidence of public health related problems associated with the use of pure CBD. A farm bill was passed in 2018 that differentiated hemp from marijuana, allowing hemp a version of marijuana grown with little or no THC to be grown and unregulated as a controlled substance

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All forms of NRT monotherapy have similar efficacy in increasing long-term cessation, compared with placebo (relative risk 1.60, 95% confidence interval 1.531.68)

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