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Key Fact: Research shows smokers look up to 10 years older than non-smokers

b , Heatmap showing associations of the smoking status with each induced cytokine following SEB stimulation when either no methylation probe (top line) or each individual methylation probe associated with IL-2 concentration levels in SEB stimulation is passed as a covariate in the models

Common Causes of Smokers Lines Often, smokers lines do not develop from a single cause

This allows diverse temporal trajectories of the studied objects and their individual heterogeneity

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