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One possible explanation provided by gene expression data in 2024 suggests that smoking is significantly associated with the upregulation of the cytokine receptor-like factor-1 (CRLF1) gene, which translates to actin alpha 2 (ACTA2+) smooth muscle cells, particularly found in carotid plaques

[296] [539] Her favorability ratings dropped, however, after she left office and began to be viewed in the context of partisan politics once more

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