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Antioxidants are often intracellular and sometimes extracellular [4]

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52 Insulin-like growth factor 1 (IGF-1) functions as both a pro-mitogenic factor and a macrophage-regulated protein, playing a crucial role in the immunomodulatory effects of mesenchymal stem cells (MSCs) and in maintaining intestinal crypt cell homeostasis

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It may also support the gut-brain axis by influencing neurochemical pathways and promoting communication between the gastrointestinal tract and central nervous system (CNS)