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However, our analysis shows that people tend to regain weight rapidly after stopping faster than we see with behavioural programmes,' says lead author Dr Sam West, postdoctoral researcher at the Nuffield Department of Primary Care Health Sciences, University of Oxford

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When the body has less energy available, it can be harder to dramatically increase strength

In particular, patients with PWS presented a chronic imbalance between higher energy intake, due to hyperphagia [9], and lower total and resting energy expenditure measured by indirect calorimetry when compared with subjects with age-, sex-, and BMI-matched controls [6]

J Plant Physiol 165(13):13901403