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Thus, F2-glutathione may directly interfere with the catalytic site of GST and glutathione

Instead, the enzyme uses a flexible C-terminal arm, which adopts different conformations during catalysis to reduce its substrates

Recently, it was demonstrated that ferroptosis blockade significantly improved the estrous cycle disorder and prolonged the estrous cycle of primary ovarian aging by intraperitoneal injection of Fer-1 in Bnc1 mutant mice, and the ratio of oxidized to reduced lipids in the ovary was significantly reduced

European Journal of Clinical Pharmacology, 50 (6), 513514