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Methylated UBE2m inhibits PPAR-mediated fatty acid metabolism by neddylating NEDD4 in TECs We further investigated how UBE2m, a key ubiquitin-conjugating enzyme essential for neddylation, regulates NEDD4-mediated PPAR ubiquitination

Stored Prod

We defined p -values below 0.0012 (0.05/42) as indicating strong evidence of associations in the MR analysis between the six endogenous antioxidants and six cancers