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FOXO4-DRI works by disrupting the interaction between the FOXO4 protein and p53, enabling p53 to activate apoptosis in senescent cells

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Considering that 42% of US adults have obesity, this is a major emotional and financial cost to the health of society and the economy

However, its also important to note that this is relative percentage increase the majority of people in the study did not change their marital status within 5 years of the surgery (i.e., we likely wont see a massive spike in divorce rates)

Addressing these limitations will necessitate coordinated advancements across scientific research, regulatory frameworks, and clinical methodologies