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O Epithalon interessante
gingivalis infection in periodontitis upregulates NCOA4 via the NF-B pathway, promoting ferritin lysosomal degradation and causing a continuous influx of ferrous iron (Fe 2+ ) into the labile iron pool (LIP) ( 2.1.2 Impaired iron efflux and pathological iron accumulation Recurrent microbleeding within the periodontal pocket is a core feature distinguishing periodontitis from other chronic inflammatory diseases and represents the most direct source of iron overload
Metabolic and energy-balance signalling
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