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WO2023012829A1 - Process for the preparation of semaglutide - Google Patents Process for the preparation of semaglutide Download PDF Info Publication number WO2023012829A1 WO2023012829A1 PCT/IN2022/050702 IN2022050702W WO2023012829A1 WO 2023012829 A1 WO2023012829 A1 WO 2023012829A1 IN 2022050702 W IN2022050702 W IN 2022050702W WO 2023012829 A1 WO2023012829 A1 WO 2023012829A1 Authority WO WIPO (PCT) Prior art keywords gly compound semaglutide glu ala Prior art date Legal status (The legal status is an assumption and is not a legal conclusion

thalidomide and lenalidomide, which modulate the production of inflammatory cytokines TNF-alpha, Il-1, IL-6, IL10, and IL-12 [4951]

You can expect that it may take 6 months or more to see meaningful changes

- The arGLP-1 s have demonstrated a CV benefit in patients with DM2 that appears to extend to patients with reduced renal function