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The most common adverse reactions were nausea, headache, vomiting, and diarrhea (108)
Cardiovascular Medicine Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
At the environmental and lifestyle level, dietary patterns [169], environmental pollutants [170, 171], physical activity habits, and smoking/alcohol consumption [172,173,174] have been shown to serve as key external triggers that precipitate or exacerbate disease through modulation of intestinal microbiota homeostasis, disruption of epithelial barrier function, and activation of oxidative stress and inflammatory pathways
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