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Men with obesity-related hypogonadism often experience improvements in testosterone levels with sustained weight reduction, though the response varies between individuals and may require weight loss greater than 5-10% in some cases
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PlexusDx's gradual dosing approach minimizes this risk by moderating weight loss velocity
For context, participants in the STEP 1 clinical trial taking 2.4 mg of semaglutide lost an average of 14.9% of their body weight over 68 weeks
Figure 3 maps the key legal events for all patents on GLP-1 receptor agonists from filing to expiration
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