semaglutide news november 2025 What the Obesity Drugmakers Expect in Novo Nordisk presents four new

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Aggregated peptide fragments can trigger injection site reactions that the native peptide does not cause

STEP Clinical Trial Program The landmark STEP (Semaglutide Treatment Effect in People with obesity) clinical trial program represents the most extensive investigation of semaglutide for weight management: STEP 1 (New England Journal of Medicine): Enrolled 1,961 adults with obesity or overweight and demonstrated a mean weight loss of 14.9% from baseline at 68 weeks with semaglutide 2.4 mg compared to 2.4% with placebo