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Zhang X, Zhao Y, Ye Y, Li S, Qi S, Yang Y, Cao H, Yang J, Zhang X (2015) Lesional infiltration of mast cells, Langerhans cells, T cells and local cytokine profiles in alopecia areata

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They are recognized by PRRs [e.g., lipopolysaccharide (LPS) from Gram-negative bacteria (recognized by TLR4), flagellin (TLR5), lipoteichoic acid and peptidoglycan from Gram-positive bacteria (TLR2), viral nucleic acids, like double-stranded RNA (TLR3) and unmethylated CpG DNA (TLR9)], triggering the innate immune response

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Suppliers benefit when researchers assume the vial 'went bad' and order replacements without examining whether the storage protocol caused the failure

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