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For example, studies have identified genes such as brain-derived neurotrophic factor (BDNF) and the serotonin transporter gene (SLC6A4) as being closely associated with depression susceptibility [292,293,294]

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Collectively, evidence for MGBA involvement in PTSD is consistent across human and preclinical studies, with strong mechanistic convergence, while interventional findings, despite early promise, remain preliminary and require validation in larger, controlled trials