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The study was funded by research on the association between genetic polymorphism of GLP1R and the efficacy of GLP1 analogues [grant numbers 201602171] and a comprehensive clinical evaluation study of GLP-1RA [grant numbers 2024YZ002]

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Available online at: 28 LiaoJ.SuguroR.ZhaoX.YuY.CuiY.ZhuY

However, it has been recently described that mTORC2 also possesses tyrosine phosphorylation capacity [118], and that it phosphorylates tyrosines on IRS and tyrosine kinases in both receptors, IGF-1 and IR, thus reinstituting the signal of the activated receptors [118]