Injections (SQ or IM) Fastest and most effective delivery method
TB-500 Promotes muscle repair, increases flexibility, and aids in injury recovery
Counteraction of the huge liver lesions (particular lesions presentation depending on the paracetamol [61], diclofenac, ibuprofen (i.e., hepatomegaly) [107], celecoxib [105], and insulin (i.e., calcification) [62]) and gastrointestinal lesions (i.e., diclofenac [108], ibuprofen [107], celecoxib [105], insulin [62]) can be a proof of the concept
Common side effects include injection site reactions (burning, pain, swelling, redness), headache, mild diarrhea, and upset stomach
There is a theoretical concern that aggressive senolytic clearance could remove this anti-tumor senescence signal, potentially accelerating tumor growth in individuals with pre-malignant cells