Id say its as bad as sprinting on a treadmill - but just think how long youd have to sprint on that treadmill to lose that same amount of fat - which would you prefer
If weight loss left you with significant loose skin, a tummy tuck is often the better fit
Some studies report increases in TMAO after supplementation in certain people, and the longterm cardiovascular significance of that finding remains an open research question.
Ongoing research includes: long-term pancreatic studies thyroid cancer surveillance 5-year cardiovascular follow-ups GI motility research safety monitoring for chronic users registries for severe GLP-1 complications FDA GLP-1 Warnings When to Call a Doctor Immediately Seek medical attention if you experience: severe abdominal pain persistent vomiting dehydration rapid weight loss inability to eat jaundice sharp back or flank pain little or no urine output These may indicate long-term GI damage, pancreatitis, or kidney injury

News provided by Pendulum Therapeutics Apr 22, 2026, 12:22 ET It is now easier than ever to shop science-backed probiotics during Sprouts Wellness Week (April 2228) SAN FRANCISCO, April 22, 2026 /PRNewswire/ -- Pendulum, the microbiome brand redefining gut and metabolic health, is now available nationwide at Sprouts Farmers Marketbringing its next-generation probiotics, including those featuring the live breakthrough strain Akkermansia muciniphila , to shelves across the country