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Dysregulated Nutrient Sensing Mitochondrial function is tightly integrated with nutrient-sensing pathways, another antagonistic hallmark governing how cells respond to energy availability

Overall, the results suggest that RRM2 acts as a pro-oncogenic molecule and may promote the progression of PTC by activating the PI3K/Akt signaling pathway, regulating key proteins of the cell cycle, and inducing the EMT process, which is in high agreement with previous findings in other malignant tumors

[PubMed: 5340761] 528

Doerks, T., Copley, R

This disorder is most correctly referred to as carnitine deficiency, systemic primary (CDSP)