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Since alpha lipoic acid is an antioxidant, much of our depleted stores go to neutralizing the free radicals that accumulate in our bodies as we age and continue to be exposed to stress and environmental toxins

Supply of these precursors might become one of the bottlenecks of the secondary metabolite biosynthesis

10.1016/s0001-706x(03)00032-9 Acta Trop

Also, it increases the death of GLP-1-producing cells through increased ceramide production, caspase-3 activity, and DNA fragmentation [140]

Abud Bakri explained on the Huberman Lab podcast, the single most important thing to understand about this category is the gap between animal data and human data