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Perhaps, multidisciplinary irAE management teams, facilitating prompt diagnosis and treatment should be enlisted

Examples include nonalcoholic fatty liver disease (NAFLD), polycystic ovary syndrome (PCOS), and neurodegenerative diseases such as Alzheimer's and Parkinson's disease [5, 6, 7, 8]

At higher doses like 10mg or 15mg , the proportional shortfall becomes larger in absolute terms