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transient blood pressure increases peak between 2 and 4 hours post-dose and return to baseline within 12 hours

All skin types (Patch test recommended)

Treatment of certain inherited disorders: Some inherited metabolic disorders, such as methylmalonic acidemia and homocystinuria, may benefit from hydroxocobalamin treatment due to its role in converting methylmalonyl-CoA to succinyl-CoA and facilitating the conversion of homocysteine to methionine

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A study in the Journal of Nutrition and Metabolism found that people who were using second-generation beta blockers (such as metoprolol and atenolol) experienced a lower percentage of weight loss than the control group, those taking third-generation beta blockers (such as carvedilol and labetalol), and those taking other antihypertensive drugs