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Kenklies, M
While the test focuses on peptide and metabolic genetic markers rather than B12-specific variants, it can reveal broader predispositions in genes like FTO and MC4R that relate to metabolic efficiency
Knieling and Othengrafen, 2009
Under the condition of stress reactions such as fever, infection, or increased metabolic stress, patients with methylmalonic acidemia may manifest symptoms of acute metabolic decompensation such as impaired level of consciousness, hypotonia complicated by hyperammonemic encephalopathy, respiratory distress, acidosis, etc
Peptide-protein conjugates combine the targeting ability of peptides with the extended half-life of proteins, potentially reducing dosing frequency while maintaining therapeutic effectiveness
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