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Cagrilintide binds to amylin receptorsheterodimeric complexes of the calcitonin receptor (CTR) with receptor activity-modifying proteins (RAMP1 or RAMP3)

Laboratory protocols demonstrate that under optimal dosing conditions, the peptide eliminates senescent cells while destroying an undetectable number of healthy cells, representing exceptional selectivity compared to earlier senolytic approaches

Automated multimodal CT analysis was performed using Brainomix software (e-stroke 10.1)

Typically, patients in their 40s to 60s benefit most, but younger individuals seeking neuroprotection can also use it preventively

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