The pharmacology is well described in the peer-reviewed literature, but clinical effect sizes vary by indication, dosing, individual factors, and adherence, which is a large part of why frequency cannot be generalized
BAC Water 30Ml is a laboratory diluent supplied for qualified research and analytical applications only
USA 107 , 34413446 (2010)
People taking heartburn medication, such as proton pump inhibitors, are at a higher risk for B12 deficiency and may benefit from alternative therapies to control/eliminate the heartburn or have regular Nutrient IV therapies and/or Vitamin B12 injections Elderly Vegans Vegetarians People with tapeworms Alcoholics Excessive use of antibiotics Excessive use of anti-convulsant medication Daily consumption of Aspirin may increase the risk for vitamin B12 deficiency
But several factors work against this natural recovery process, including age (collagen production drops roughly 1% per year after age 20), the amount of weight lost (more than 50 pounds creates significantly more laxity), how long the excess weight was carried, sun damage history, smoking, genetics, and the speed at which the weight came off