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Evidence from these studies, along with data potentially arising from the use of tirzepatide in patients with T2D, obesity and coexisting autoimmune diseases, could help fill the current knowledge gap regarding GIP targeting in chronic inflammatory conditions
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Patients with eGFR below 30 mL/min/1.73m require careful monitoring and may maintain lower maintenance doses, though tirzepatide is not contraindicated in mild to moderate renal impairment
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