Preliminary results from a study conducted with pregnant beef cows in late gestation reported increased maternal plasma MET concentrations in cows fed RPM and lower concentrations in those supplemented with GAA, with intermediate values in cows receiving both RPM + GAA (Motta et al., 2025), highlighting the role of GAA as a methyl consumer
A 2021 review of studies noted that digestive side effects like nausea are often mild to moderate and tend to sharply decrease after week 20 of treatment
Similarly, 63-year-old Demi Moore made a head turn at the Dior fashion show where she was criticised for looking extremely thin and unhealthy
Furthermore, AI and machine learning methodologies can be incorporated for real-world data analysis such as for surveying social media trends for better understanding of patient experiences and misconceptions about GLP-1 RAs, in identification of potential treatment barriers like insurance coverage limitations and concerns regarding side effects for developing targeted interventions and also in evaluation of treatment efficacy in real-world settings
WFJH designed and synthesized all fluorescently labelled peptides used in the studies, and contributed to discussions of study designs and data