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In particular, fibrosarcoma, a typical tumor with a little-known relationship with the ovary, can increase plasma CXCL10, which reaches the ovaries, binds to IL18R1 on the ovaries, and triggers multiple downstream ovary-disrupting signals

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Xiao B, Si X, Han MK, Viennois E, Zhang M, Merlin D (2015) Co-delivery of camptothecin and curcumin by cationic polymeric nanoparticles for synergistic colon cancer combination chemotherapy

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Cancer metabolism is a factor that might be exploited as a potential therapeutic target for drug discovery also on how a cancer cell differs in its metabolism to that of a rapidly proliferating normal cell (Vander Heiden et al