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(Source: In August 2025 , Viking Therapeutic announced encouraging mid-stage trial results for its experimental oral/injectable weight loss drug VK2735, which achieved up to 12.2% body weight reduction over 12 weeks, through shares dropped due to higher treatment discontinuation from gastrointestinal side effects

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These multifaceted effects position GLP-1RAs as a promising therapeutic option in MASLD, thus warranting further investigation through clinical trials