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While safety data is encouraging, with no significant differences in adverse events compared to placebo, a larger Phase IV outcomes trial is ongoing to confirm the long-term cardiovascular benefits of enlicitide, and Merck has initiated the FDA approval process, with the drug in the fast track program

In older persons, walking discomfort, functional impairment, and lower satisfaction scores are linked to elevated inflammatory markers such as C-reactive protein (CRP)

Liver Int 29(8):11841188

During the progress, the actual body weight variation of mice was closely monitored

The study authors said they hope their findings prompt regulatory agencies and drug manufacturers to update warning labels for the medication and include gastroparesis as a potential side effect