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DPP-4 inhibitors A variety of DPP-4 inhibitors are available, differing in dosing frequency, metabolism, and excretion pathways, allowing for individualized selection based on renal function, liver function, and lifestyle considerations in individuals with type 2 diabetes (Fig

Despite extensive research highlighting their neuroprotective, antioxidant, anti-inflammatory, antibacterial, dermatological, antitumor, and antidiabetic properties, the underlying mechanisms remain only partially understood

References: Patel et al

What I saw in the Phase 2 trial data was that participants with type 2 diabetes required significant insulin dose adjustments as retatrutide took effect

Such collaborative care models, which may involve dietitians, physical therapists, and pharmacists, enhance patient education and foster adherence to the prescribed GLP-1 regimen, ultimately supporting better health outcomes