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doi:10.1039/C5CS00838G Lilius H, Hastbacka T, Isomaa B (1995) A comparison of the toxicity of 30 reference chemicals to Daphnia magna and Daphnia pulex

In 2018, Amazentis SA received a favorable Generally Recognized As Safe (GRAS) review of Mitopure from the FDA

All proposed interventions should be evaluated against their potential to reduce the incidence and prevalence of AD/ADRD, as well as inequalities

The situation is not entirely conclusive since knock-out of the CCK-1 receptor in mice does not result in a similar phenotype

Each compound is supplied with documented purity specifications and certificates of analysis, supporting reproducible preclinical protocols