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The improvements we observed are consistent across multiple health systems and patient populations, including groups historically underrepresented in clinical trials. New York Heart Association class, and outflow tract gradients fell by 35-59 mmHg on average, bringing most patients below guideline thresholds for obstruction

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The patient reported dysphagia and belching, which were also present even before the initiation of semaglutide treatment, and these symptoms resolved spontaneously in the following months

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PeerJ 4:e2127 Salama M, Elgamal M, Abdelaziz A, Ellithy M, Magdy D et al (2015) Toll-like receptor 4 blocker as potential therapy for acetaminophen-induced organ failure in mice