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Researchers enrolled 17,604 adults who: were 45 years or older had overweight or obesity (BMI 27) already had heart disease (such as a prior heart attack, stroke, or peripheral artery disease) did not have diabetes Participants were randomly assigned to receive either: semaglutide 2.4 mg weekly, or a placebo (an injection with no active medication) They were followed for about 40 months (over 3 years)

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Obesity rates are rising even among poorer, developing countries

Here's what the evidence says

These include major chain pharmacies and licensed mail-order services