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Metformin in Non-Alcoholic Steatohepatitis

Our results are also consistent with publications showing that CAV-1 reduction upregulates angiogenesis-related factors as evidenced by an inverse correlation between CAV-1 and VEGF in osteosarcoma 28 , increased CXCR12 expression in CAV-1 silenced fibroblast 29 , and a significant negative correlation between osteopontin and caveolin-1 levels in human osteoarthritic cartilage 30

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Improper dosage may also lead to unpleasant side effects like nausea, vomiting, or diarrhea

The condition is most common in those over age 40 and athletes