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Int J Mol Sci 20(8):1930 Contreras-Angulo LA, Emus-Medina A, Bernal-Millan M, Heredia JB, & Gutirrez-Grijalva EP

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Furthermore, exercise training induces a robust increase in the skeletal muscle of NAMPT protein in sedentary nonobese subjects

To assess the clinical relevance of serine metabolism in lung cancer, we analyzed TCGA data and observed significant upregulation of key serine synthesis enzymes (PHGDH, PSAT1, PSPH, SLC1A4) and transporters (SLC2A1, SLC1A4, SLC1A5) in tumors compared to normal tissues (Fig

They exert their effects by binding to their specific G-protein-coupled receptors, C3aR and C5aR, respectively (119)