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American Academy of Neurology guidelines on treating painful DPN recommend that clinicians evaluate oral, topical and nonpharmacologic therapies for patients with painful diabetic polyneuropathy, and emphasizes switching between drug classes rather than trying multiple agents within the same class if one fails [63]

But as a clinician, we're thinking of someone with overweight or obesity

Tirzepatide: A dual GIP/GLP-1 agonist that works on a number of metabolic pathways to help regulate hunger and improve insulin sensitivity

The benefit of gastric lavage or emesis will vary with the time since ingestion

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