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GLP-1 receptor agonists as a drug class have substantial clinical trial evidence supporting significant weight loss outcomes, with peer-reviewed research demonstrating statistically meaningful reductions in body weight in large randomized controlled trials

doi: 10.1111/imj.13104 [PubMed] 28489461 Levine M, Stellpflug S, Pizon AF, Traub S, Vohra R, Wiegand T, Traub N, Tashman D, Desai S, Chang J, Nathwani D, Thomas S