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Alcohol stresses the liver cells, which can temporarily impair their ability to produce and recycle this essential antioxidant
Front Cell Dev Biol 7:50 Sprooten J, De Wijngaert P, Vanmeerbeek I, Martin S, Vangheluwe P, Schlenner S, Krysko DV, Parys JB, Bultynck G, Vandenabeele P, Garg AD (2020) Necroptosis in immuno-oncology and cancer immunotherapy
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As suggested by the authors of both study groups, the observed differences in redox imbalance between the salivary glands of rats exposed to ethanol intake in a binge model were caused by the different morphology of the two glands as well as the fact that the parotid glands, unlike the aerobic submandibular glands, have an aerobic metabolism, which predisposes them to greater exposure and damage by ROS
It is not chemically identical to full-length 43-residue thymosin beta-4
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