Therapeutic Applications and Research Congenital Hyperinsulinism In congenital hyperinsulinism due to inactivating mutations in the ATP-sensitive K+ channel (KATPHI), exendin-(9-39) has been shown to elevate fasting blood glucose levels by suppressing insulin secretion
HELPS DIGESTION & SUSTAINS ENERGY Bloating, irregular digestion, and energy dips can be challenges when following a GLP-1 lifestyle
I totally agree that the unethical compounders & outfits like HIMS which imho have grossly misled the public should be nailed, but there are compounders who are trying to follow FDA promulgations on stuff like this who get lumped in inappropriately imho
Similarly, cancer immunotherapy patches might co-deliver tumor neoantigens plus TLR agonists or PD-1 inhibitors, creating a localized cocktail that primes dendritic cells and modulates the tumor microenvironment simultaneously
A RCT in a small group of obese T2DM patients with FGF-21 found significant improvement in lipid profiles as well as weight loss, reduced insulin levels, and raised adiponectin [84]