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Cell culture The mouse pancreatic -cell line, Min6, was cultured in DMEM high glucose medium containing 10% fetal bovine serum

Immunohistochemical staining and western blot analysis revealed that SNL increased the activation of microglia and astrocytes in the dentate gyrus of the hippocampus, along with elevated expression of pro-inflammatory cytokines such as TNF-, IL-1 and IL-6, which were significantly reversed by exendin-4 treatment [68]

Some of the most effective GLP-1 foods rich in fermentable fiber include: Oats and barley Lentils and chickpeas Apples and pears Chia seeds and flaxseeds Artichokes and broccoli When these foods appear regularly in the diet, they nourish both the gut microbiome and the hormonal signals that regulate hunger