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Rushing the injection creates a high-pressure bolus of medication that mechanically disrupts tissue and triggers a stronger inflammatory response

When platelets are not sticky, they can move in a single file through the capillaries

What happened: The 503B Bulks List proposal On April 30, 2026, the FDA announced it is proposing to exclude semaglutide, tirzepatide, and liraglutide from the 503B Bulk Drug Substances List

The figure was adapted from Mayr et al